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Project
Patient-Specific Planning of Transarterial Drug Delivery for Liver Cancer: Modelling Drug Particle Transport and Catheter Accessibility
Information
Project Team
Outputs and Outcomes
Publications
Simplification strategies for a patient-specific CFD model of particle transport during liver radioembolization
Tim Bomberna
Geert Maleux
Charlotte Debbaut
U
Journal Article
in
COMPUTERS IN BIOLOGY AND MEDICINE
2024
Adaptive design of experiments to fit surrogate Gaussian process regression models allows fast sensitivity analysis of the input waveform for patient-specific 3D CFD models of liver radioembolization
Tim Bomberna
Geert Maleux
Charlotte Debbaut
A1
Journal Article
in
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
2024
Spatiotemporal analysis of particle spread to assess the hybrid particle-flow CFD model of radioembolization of HCC tumors
Tim Bomberna
Saar Vermijs
Lawrence Bonne
Chris Verslype
Geert Maleux
Charlotte Debbaut
A1
Journal Article
in
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
2024
Truncation strategies for personalized CFD models of selective liver radioembolization
Tim Bomberna
Saar Vermijs
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
C3
Conference
2023
Computational fluids dynamics to investigate the impact of injection timing and location on microsphere and microbubble distribution in a simplified hepatic arterial tree
Tim Bomberna
Nathalie Saikali
Romaine Kunst
Hadi Mirgolbabaee
Erik Groot Jebbink
Geert Maleux
Charlotte Debbaut
C3
Conference
2022
Computational modelling of liver hemodynamics and intrahepatic particle transport
Charlotte Debbaut
Tim Bomberna
C3
Conference
2022
The impact of hepatic arterial tree complexity on microparticle transport in computational fluids dynamics simulations of radioembolization for hepatocellular carcinoma
Tim Bomberna
Saar Vermijs
Maryse Lejoly
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
C3
Conference
2022
The impact of injection timing, injection velocity and inflow waveform on microsphere transport during liver radioembolization
Tim Bomberna
Saar Vermijs
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
C1
Conference
2022
The future of preoperative planning for liver cancer : from CT-scan in the 20th century to computational model in the 21st century
Tim Bomberna
Charlotte Debbaut
C3
Conference
2022
Assessment of hepatic arterial hemodynamics with 4D flow MRI : in vitro analysis of motion and spatial resolution related error and in vivo feasibility study in 20 volunteers
Ivan P. Dimov
Cyril Tous
Ning Li
Maxime Barat
Tim Bomberna
Charlotte Debbaut
Ning Jin
Gerald Moran
An Tang
Gilles Soulez
A1
Journal Article
in
EUROPEAN RADIOLOGY
2022
A hybrid particle-flow CFD modeling approach in truncated hepatic arterial trees for liver radioembolization : a patient-specific case study
Tim Bomberna
Saar Vermijs
Maryse Lejoly
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
A1
Journal Article
in
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
2022
The impact of catheter location on tumor dose distribution for liver cancer radioembolization
Tim Bomberna
Saar Vermijs
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
C3
Conference
2022
Numerical modelling in support of locoregional drug delivery during transarterial therapies for liver cancer
Charlotte Debbaut
Tim Bomberna
Bookchapter
in
Modelling of mass transport processes in biological media
2022
Proof-of-concept CFD model to improve hepatic arterial tree recellularization protocols
Tim Bomberna
Ghazal Adeli Koudehi
Pedro Baptista
Charlotte Debbaut
C3
Conference
2021
Comparing time-efficient particle release maps for liver tumor targeting with embolizing microparticles
Tim Bomberna
Geert Maleux
Charlotte Debbaut
C3
Conference
2021
Evaluating the impact of catheter type on local hemodynamics to improve transarterial liver cancer treatments
Tim Bomberna
Ghazal Adeli Koudehi
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
C3
Conference
2021
The impact of injection timing and location on microparticle delivery for tumor targeting in a patient-specific liver
Tim Bomberna
Chris Verslype
Lawrence Bonne
Geert Maleux
Charlotte Debbaut
C3
Conference
2021
Transarterial drug delivery for liver cancer : numerical simulations and experimental validation of particle distribution in patient-specific livers
Tim Bomberna
Ghazal Adeli Koudehi
Charlotte Claerebout
Chris Verslype
Geert Maleux
Charlotte Debbaut
A1
Journal Article
in
EXPERT OPINION ON DRUG DELIVERY
2021
Computational fluid dynamics as a tool for patient-specific injection planning of transarterial therapies for hepatocellular carcinoma
Tim Bomberna
Chris Verslype
Geert Maleux
Charlotte Debbaut
C3
Conference
2020
Locoregional drug delivery for liver cancer : the impact of tumor burden on the particle distribution in a patient-specific liver
Tim Bomberna
Ghazal Adeli Koudehi
Geert Maleux
Charlotte Debbaut
C3
Conference
2020
Targeted drug delivery for liver cancer : modelling the impact of cancer burden on the particle distribution
Tim Bomberna
Ghazal Adeli Koudehi
Patrick Segers
Charlotte Debbaut
C3
Conference
2020
Targeted drug delivery for liver cancer : can we steer microparticles towards tumor tissue?
Tim Bomberna
Ghazal Adeli Koudehi
Patrick Segers
Charlotte Debbaut
C3
Conference
2020
Targeted drug delivery for liver cancer : the impact of cancer burden on the particle distribution in a patient-specific geometry
Tim Bomberna
Ghazal Adeli Koudehi
Patrick Segers
Charlotte Debbaut
C3
Conference
2019