Research Explorer

Project

Study of direct cell-to-cell transfer of hepatitis C virus and evaluation of new antiviral strategies
Code
31500910
Duration
01 January 2010 → 31 December 2012
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
Keywords
prevention HCV immunotherapy liver transplantation viral hepatitis
 
Project description
 

End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is the major indication for liver transplantation in the Western world. Unfortunately, almost immediately after transplantation the circulating viruses will infect the donor liver resulting in destruction of the grafted organ within 5 years. In this project we will explore new strateies to prevent the transmission of this virus.