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Project

Single cell approaches for the study of early human T cell development

Information

Project Team

Outputs and Outcomes

Publications

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

Kai Ling LiangJuliette RoelsMarieke LavaertTom PuttemanLena BoehmeLaurentijn TillemanImke VelgheValentina PegorettiInge Van de WalleStephanie SontagJolien VandewalleBart VandekerckhoveGeorges LeclercqPieter Van VlierbergheClaude LibertFilip Van NieuwerburghRoman FischerRoland E. KontermannKlaus PfizenmaierGina DoodyMartin ZenkeTom Taghon et al.

A1 Journal Article in NATURE IMMUNOLOGY

2023

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

Juliette RoelsJolien Van HulleMarieke LavaertAnna KuchmiySteven StrubbeTom PuttemanBart VandekerckhoveGeorges LeclercqFilip Van NieuwerburghLena BoehmeTom Taghon et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2022

Development of gamma delta T cells in the thymus : a human perspective

Lena BöhmeJuliette RoelsTom Taghon

A1 Journal Article in SEMINARS IN IMMUNOLOGY

2022