Research Explorer

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Project

Clinical validation of new targets for the inhibition of HIV replication.

Outputs and Outcomes

Publications

Development of human innate immune responses in a humanized mouse model expressing four human myelopoiesis transgenes

Hannah StocksElisabeth De LeeuwBart LambrechtLinos VandekerckhoveGeert van LooAndy Wullaert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Longitudinal patterns of inflammatory mediators after acute HIV infection correlate to intact and total reservoir

Jozefien De ClercqMarie-Angélique De ScheerderVirginie MortierChris VerhofstedeStefaan J. VandecasteeleSabine D. AllardCoca NecsoiStephane De WitSarah GerloLinos Vandekerckhove

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir

Marion PardonsBasiel ColeLaurens LambrechtsWillem van SnippenbergSofie RutsaertYtse NoppeNele De LangheAnnemieke DhondtJerel VegaFilmon EyassuErik NijsEllen Van GulckDaniel BodenLinos Vandekerckhove et al.

A1 Journal Article in NATURE COMMUNICATIONS

HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization

Laurens LambrechtsNoah BonineRita VerstraetenMarion PardonsYtse NoppeSofie RutsaertFilip Van NieuwerburghWim Van CriekingeBasiel ColeLinos Vandekerckhove

A1 Journal Article in NUCLEIC ACIDS RESEARCH

No significant association between 25-OH vitamin D status and SARS-VoV-2 antibody response after COVID-19 vaccination in nursing home residents and staff

Eline MeyersEvelien De SmetHanne VercruysseSteven CallensElizaveta PadalkoStefan HeytensLinos VandekerckhovePiet CoolsWojciech Witkowski

A1 Journal Article in VACCINES

Evaluating lncRNA expression patterns during HIV-1 treatment interruption

Tinus SchynkelWillem van SnippenbergClarissa Van HeckeLinos VandekerckhoveWim Trypsteen

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption

Basiel ColeLaurens LambrechtsZoe BoyerYtse NoppeMarie-Angélique De ScheerderJohn-Sebastian EdenBram VranckenTimothy E. SchlubSherry McLaughlinLisa M. FrenkelSarah PalmerLinos Vandekerckhove et al.

A1 Journal Article in CELL REPORTS

Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature

Magdalena SipsSarah GerloLaura De ClercqEsteban A. GomezRomain A. ColasJesmond DalliLinos Vandekerckhove

A1 Journal Article in IMMUNITY INFLAMMATION AND DISEASE

Measuring proviral HIV-1 DNA : hurdles and improvements to an assay monitoring integration events utilising human alu repeat sequences

Eva MalatinkováJordan ThomasWard De SpiegelaereSofie RutsaertAnna Maria GerettiGeorgios PollakisWilliam A. PaxtonLinos VandekerckhoveAlessandra Ruggiero

A1 Journal Article in LIFE-BASEL