Project

Investigating the pathofysiology of stroke and poststroke epilepsy

Code
bof/baf/1y/2024/01/064
Duration
01 January 2024 → 31 December 2024
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Neurological and neuromuscular diseases
    • Neurological and neuromuscular diseases
Keywords
Stroke epilepsy Spontaneous intracerebral hemorrhage
 
Project description

Stroke is one of the leading causes of disability and mortality worldwide. The two main types of stroke are ischemic stroke (IS) 
and intracerebral hemorrhage (ICH). Epilepsy is a chronic neurological disease and is defined as the occurrence of epileptic 
seizures. Epileptic seizures are clinical manifestations resulting from excessive synchronous, abnormal firing patterns of neuro
ns that are located predominantly in the cerebral cortex. Epileptic seizures are common following a stroke, but the underlying 
pathofysiology of post-stroke seizures is unknown. Using electrophysiological techniques combined with multimodal imaging 
and clincal data, my group is investigating the pathofysiology and associated factors of seizures following stroke in patients 
as well as in preclinical animal models.