Development of an easy-to-use test to diagnose and subtype lymphoma in veterinary medicine

01 May 2024 → 30 June 2025
Regional and community funding: Industrial Research Fund
Research disciplines
  • Medical and health sciences
    • Development of bioinformatics software, tools and databases
    • Clinical genetics and molecular diagnostics
  • Agricultural and food sciences
    • Animal health engineering
    • Veterinary genetics
whole genome sequencing Diagnostics third generation sequencing oncology companion animals canine lymphoma
Project description

With technological advances, the challenge for researchers in genetics has shifted from investigating (epi)genetic alterations at a large scale to translating these findings to clinic. Implementations in veterinary oncology are however almost non-existing.  

To tackle this, canine multicentric lymphoma is the ideal disease to work on: it has a high prevalence and different subtypes with variable prognosis. With the current sequencing technologies, various molecular alterations that are known to be associated with tumour behaviour can be investigated. This technique will be used to develop an easy-to-use test, with various improvements compared to the current standards, including easier sampling, no need for specialized equipment, a short turnaround time and efficient clinical reporting. Altogether, the successful development would be a major step forward in veterinary oncology in general and for canine lymphoma.