Research Explorer

Project

A precision medicine approach for canine degenerative myelopathy combining genetic and epigenetic alterations
Code
01N04119
Duration
01 January 2019 → 31 December 2022
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal genetics
    • Epigenetics
    • Epigenomics
  • Social sciences
    • Neuropsychology
    • Neurocognitive patterns and neural networks
    • Cognitive aging
  • Medical and health sciences
    • Epigenetics
    • Neurological and neuromuscular diseases
    • Neurological and neuromuscular diseases
    • Epigenetics
    • Neurophysiology
  • Agricultural and food sciences
    • Veterinary genetics
    • Other veterinary sciences not elsewhere classified
    • Agricultural and food sciences not elsewhere classified
Keywords
Precision medicine (epi)genetics degenerative myelopathy
 
Project description
 

This project aims to introduce precision medicine and epigenetics research in the canine neurogenetics field. Practically, canine degenerative myelopathy will be studied with MBD-seq to identify differentially methylated regions associated with disease progression. This will be followed by the writing of a general statistical analysis framework in R that accurately predicts clinical age ofonset for this disorder.