Project

Exploring the role of mini-proteins and toxin antitoxin-modules in Burkholderia cenocepacia biofilm formation and persistence

Duration
01 October 2014 → 30 September 2018
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
Burkholderia persistence toxin antitoxin module biofilm mini-proteins
 
Project description

B. cenocepacia is an opportunistic pathogen that can cause lung infections in cystic fibrosis patients. While previous research has predominantly focussed on larger proteins, evidence is accumulating that polypeptides (< 200 amino acids) are involved in various biological processes. The goal of the present study is to elucidate involvement of mini-proteins and toxin antitoxin-modules in B.cenocepacia biofilm formation and persistence.