Code
01CD06024
Duration
01 November 2024 → 30 April 2025
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Biomarker discovery
- Kidney diseases
-
Agricultural and food sciences
- Veterinary internal medicine and pathophysiology
Keywords
optimization
biomarkers
validation
profiling
fingerprinting
feline chronic kidney disease
Metabolomics
Project description
Early biomarkers for feline chronic kidney disease (CKD) are lacking. This study: (i) aims to optimize and validate a serum and urine UHPLC-HRMS protocol, ii) leverages the power of (un)targeted metabolomics to discover novel biomarkers in both matrices and iii) validates the selected markers and panels in a longitudinal cohort of healthy cats that developed CKD.