Project

The role of matrix metalloproteinases in neuro-inflammation in mesial temporal lobe epilepsy and febrile seizures

Code
3G016807
Duration
01 January 2007 → 30 December 2012
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Laboratory medicine
    • Neurosciences
    • Laboratory medicine
    • Neurosciences
    • Laboratory medicine
    • Neurosciences
Keywords
animal matrix metalloproteinases (MMPs) epilepsy
 
Project description

The project will investigate the role of matrix metalloproteinases (MMPs) in mesial temporal lobe epilepsy (MTLE) and febrile seizures. MMP analysis will be performed on human hippocampal tissue and cerebrospinal fluid from persons with and without MTLE. The role of MMPs and the effect of different treatment modalities will als be investigated in 2 animal models.