Development of silica templating approaches allowing in-column polymerization of low domain size polymer monoliths for liquid chromatography applications

01 October 2017 → 30 September 2021
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Analytical chemistry
    • Macromolecular and materials chemistry
  • Medical and health sciences
    • Pharmaceutical analysis and quality assurance
Chromatography HPLC monolith template polymer
Project description

This project intends to use HPLC columns packed with porous silica material as templates for in-column polymerization allowing the fabrication of more efficient monolithic chromatographic columns. Preliminary work showed that it is possible to perform free radical polymerizations inside the pores of porous silica material. The polymerization of the inner and interconnecting pores and of the through pores is envisaged.