Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

Molecular design of imidazole enhanced nucleic acid aptamers and DNAzymes based upon a modeling-synthesis-analysis toolbox

Outputs and Outcomes

Code

01J15317

Duration

01 October 2017 → 30 September 2021

Funding

Regional and community funding: Special Research Fund

Promotor

José Martins

Research disciplines

Natural sciences
- Analytical chemistry
- Organic chemistry
- Biochemistry and metabolism
Medical and health sciences
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism

Keywords

DNA aptamer NMR structure analysis bioorganic synthesis sensing catalysis

Project description

integrated approach comprising in silico modelling, chemical synthesis and analysis using NMR of nucleic acids is further developed, expanded and subsequently applied for the development of small molecule binding aptamers and catalytic DNA structures or so called DNAzymes.

English

Dutch

English

Cookie settings

In addition to functional cookies which are necessary for the website to function, Ghent University uses non-functional cookies such as statistical cookies and social media cookies. These non-functional cookies can also be placed by third parties, for example to measure the use of the site or to share content on social media. Certain media are only available if you accept the cookies. You can set and modify your cookie preferences yourself. Find out what cookies we use and why in the Cookie Statement.

Analytics

AnalyticsWe'll collect information about your visit to our site. It helps us understand how the site is used – what's working, what might be broken and what we should improve.

Powered by