PATHWAYS’ aim is to inform policy, research and business strategies in support of a transition to more sustainable livestock production and consumption. We will achieve this through improved characterisation and assessment of current livestock systems through refined and new indicators, the identification of the trade-offs and synergies of innovations, and through the evaluation of sustainable development scenarios to derive credible, relevant and effective transition pathways. To reach our aim, we have brought together the best scientific expertise in Europe across disciplines, including animal welfare, environmental and economic assessment and policy analysis, to develop novel and scientifically supported holistic sustainability assessment methodologies to identify the best current and future production systems and value chains. Collaboration and co-design with industry stakeholders will ensure relevance and maximise the uptake of innovations. National practice hubs and a European multi-actor platform will allow for an engaged co-design of transition pathways whilst innovative living labs will allow for the testing and sharing of innovative solutions. A community of practice will extend the multi-actor approach to a broad range of stakeholders