Research Explorer

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Project

Evaluation of new tools to study the HIV latent reservoir in vitro and in vivo

Outputs and Outcomes

Code

01N02712

Duration

01 January 2012 → 31 March 2017

Funding

Regional and community funding: Special Research Fund

Promotor

Linos Vandekerckhove

Research disciplines

Medical and health sciences
- Immunology not elsewhere classified

Keywords

HIV next generation sequencing integration target capture laser capture microdissection

Project description

In this project new tools will be optimized to investigate latent HIV infection in vivo. Integration sites will be analyzed by optimizing a technique for sequence specific capture and DNA sequencing of proviral HIV DNA. In addition, a technique to identify latently infected cells based on in situ hybridization will be optimized for laser capture microdissection and gene expression analysis.

English

Dutch

English

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