Project

Postdoctoral Fellowship Program in National Glaucoma Research: "“Exploring ICG-mediated ILM photodisruption as a tool to boost retinal ganglion cell engraftment"

Code
42S03423
Duration
01 July 2023 → 30 June 2025
Funding
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Other pharmaceutical sciences not elsewhere classified
Keywords
inner limiting membrane photoporation stem cell transplantation
 
Project description

This project explores an innovative biophotonic approach to manipulate the inner limiting membrane (ILM), a barrier which greatly
hinders the retinal entry of donor retinal ganglion cells (RGCs) following intravitreal injection. By controlled perforation of the ILM, we aim to enhance the
migration of RGCs into the retina while maintaining ILM’s cues necessary for their subsequent integration and development.