Research Explorer

Project

Research towards the molecular pathogenesis of chlamydophila psittaci in human macrophages and epithelial cells: genomics, proteomics and methylomics of highly and less virulent strains.
Code
01J05810
Duration
01 May 2010 → 30 April 2016
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Bacteriology
    • Transcription and translation
  • Engineering and technology
    • Other biotechnology, bio-engineering and biosystem engineering not elsewhere classified
Keywords
bioinformatics biotechnology microbiology
 
Project description

The project aims at getting more insight into the bacterium host cell interactions, focusing on the molecular pathogenesis en reprogrammation of the host cell by this obligate intracellular bacterium. For that purpose we can make use of well identified chlamydophila psittaci strains with well documented differences in virulence demonstrated both in vitro and in vivo.