Project

Engineering anti-cancer immunity using polymeric nanoparticles that transform into synthetic cell surface receptors in response to intracellular pH

Acronym
3g092517
Duration
01 January 2017 → 31 December 2020
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Other paramedical sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
Keywords
cancer
 
Project description

The aim of this project is to develop nanoparticles that – upon targeted uptake by tumor cells – disassemble into soluble polymers. Subsequently, these polymers will position themselves on the cell surface and bind to endogenous antibodies, thereby provoking an immune response against the tumor cells.