Synthesis of therapeutically useful compounds featuring branched-chain carbohydrate moiety

01 October 2013 → 30 September 2017
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Organic chemistry
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
Branched-chain sugars nucleoside analogues
Project description

This project aims at exploring branched-chain sugars (apiose, hamamelose) as building blocks for the synthesis of compound (libraries) with therapeutic potential, more precisely

- potentiators of antibiotics

- nucleosides with antiviral activity

- scaffolds for protein-protein dysruptors