Code
365O9110
Duration
01 January 2011 → 31 December 2014
Funding
Funding by bilateral agreement (private and foundations)
Promotor
Research disciplines
-
Natural sciences
- Systems biology
-
Medical and health sciences
- Hematology
- Laboratory medicine
- Medical systems biology
- Hematology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Hematology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
Keywords
tumor suppressor
PHF6
T-ALL
leukemia
T-cell
Project description
T-ALL results from the malignant transformation of thymocytes and mainly affects children. Recently, PHF6 was identified as a novel tumor suppressor gene in T-ALL at the Center of Medical Genetics Ghent. The aim of this project is to investigate the role of PHF6 in the development of normal T-cells and T-ALL and to unravel transcriptional networks regulated by PHF6