Gold nanoparticle templated vaccine nanocarriers

01 March 2013 → 30 September 2016
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
  • Engineering and technology
    • Biomaterials engineering
    • Ceramic and glass materials
    • Materials science and engineering
    • Semiconductor materials
    • Other materials engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
gold nanoparicles vaccines dendritic cells
Project description

Dendritic cells (DC) are the key players linking annate to adaptive immunity and the development o nanocarriers that can target and activate these cells while delivering an antien payload is believed to be o high importance in the development of the next generation of vaccines against intracellular pathogens and for the development of anti-cancer cavvines. here we aim to design nanovaccines based on gold nanoparticles with sezes ranging from 10-100 nm and decorated with antigen, DCC-targeting and DC-activating ligands.