Brain health is the state of brain functioning across cognitive, sensory, social-emotional, behavioural and motor domains, allowing a person to realize their full potential over the life course, irrespective of the presence or absence of disorders. The global population’s brain health is at risk with a ever increasing number of people developing brain disorders.

Neuromodulation is a rapidly-growing research field encompassing a wide spectrum of implantable and non-invasive technology-based approaches for the treatment of neuropsychiatric disorders. Neuromodulation refers to interfacing and intervening with the nervous system through electrical, magnetic and ultrasound energy, chemical, opto- and and electroceutical methodologies with the goal of long-term activation, inhibition, modification, and/or regulation of neural activity in order to preserve normal functioning or cure a diseases state.

The aim of this project is to develop strategies to maintain people’s brainhealth and cure brain disorders with the use of the most novel technologies that induce neuromodulatory changes in the brain. For this purpose the determinants of brain health need to be identified, the mechanism of action of the various neuromodulatory techniques need to be elucidated and personalized approaches need to be developed to maintain individual’s brain health or treat brain disorders.