Project

Analysis of chromosomal radiosensitivity/instability in triple negative and/or young breast cancer patients and patients with Fanconi anemia from South Africa

Duration
01 October 2015 → 30 September 2019
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Medicinal and biomolecular chemistry
    • Genetics
    • Molecular and cell biology
    • Plant biology
    • Systems biology
  • Medical and health sciences
    • Biophysics
    • Laboratory medicine
    • Medical imaging and therapy
    • Medical systems biology
    • Molecular and cell biology
    • Biophysics
    • Laboratory medicine
    • Medical imaging and therapy
    • Medical systems biology
    • Molecular and cell biology
    • Biophysics
    • Laboratory medicine
    • Medical imaging and therapy
    • Medical systems biology
    • Molecular and cell biology
Keywords
triple negative breast cancer chromosomal radiosensitivity young breast cancer DNA repair Fanconi anemia
 
Project description

Chromosomal radiosensitivity has been observed in breast cancer patients in European populations and is linked with DNA repair pathways. As triple negative, young breast cancer and Fanconi anemia patients frequently have defects in these pathways , the chromosomal radiosensitivity, instability and the link with DNA repair genes will be investigated in these patients.