Research Explorer

Project

Importance of low fluid shear in the interaction between microbe and host

Code
31526012
Duration
01 January 2012 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Microbiology
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Microbiology
Keywords
gut wall gut microbiota mucosa
 
Project description
 

Mucosal bacteria in teh gut make close contact with the host and thereby have a large potential to influence health. In the mucosal environment specific laminar flow patterns and low fluid shear stresses are prevailing that lead to altered gene expression in both the microbe as teh host. Adapted in vitro technology now makes it possible to mimic these conditions and investigate the consequences for the microbe host relationship.