Project

FWO junior vis. Postdoc Fellowship Sastry Mudiganti

Duration
01 February 2007 → 30 January 2010
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Organic chemistry
    • Other chemical sciences
  • Agricultural and food sciences
    • Agricultural plant production
Keywords
quinones pentalongin aza-antraquinones mollugin
 
Project description

Synthesis of nitrogen analogues of naturally occurring pyranonaphtopquinones, 2-aza-antraquinones en related compounds. Asymmetric synthesis of target compounds (trans-dihydroxymollugin viaepoxides, cis-dihydroxymollugin and isagarin via asymmetric dihydroxylation). Oxidation protocols based on cerium(IV) ammonium nitrate. Bio-activity tests, screening for antifungal and antitubercular activities.