Code
3F022008
Duration
01 October 2008 → 30 September 2012
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- Organic chemistry
-
Medical and health sciences
- Morphological sciences
- Oncology
- Morphological sciences
- Oncology
- Morphological sciences
- Oncology
Keywords
synthesis
flavonoïds
anti-invasive agents
chalcones
QSAR
Project description
Invasion and metastasis are the foremost causes of the fatal outcome of cancer and accordingly pose a main challenge in oncology. Using a predictive QSAR-model as a rationale and an in vitro assay as verification, the objective of this project is to synthesise new potent anti-invasive agents amongst the classes of chalcones and related heterocyclic compounds.