Code
01CD10023
Duration
01 November 2023 → 30 April 2024
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Analysis of next-generation sequence data
- Computational transcriptomics and epigenomics
- Molecular biophysics
Keywords
androgen receptor
biomarker
Cell-free RNA
liquidbiopsies
cell-free DNA
advanced cancer
Project description
Advanced tumours relapse and show different resistance mechanisms. Because tissue biopsies are discomforting for patients our focus is on liquid biopsies (plasma). We will detect alterations in circulating DNA as prognostic biomarkers in the context of radiotherapie +/- immunotherapie. Circulating RNA will be investigated in the context of resistance to hormonal therapy in advanced prostate cancer.