Research Explorer

Project

Immunoediting and immune evasion mechanisms in the treated and untreated cancer genome
Code
01N13819
Duration
01 May 2019 → 29 February 2024
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Bioinformatics and computational biology not elsewhere classified
  • Medical and health sciences
    • Oncology not elsewhere classified
Keywords
Cancer immunoediting immune evasion tumour evolution somatic mutations
 
Project description
 

Tumour-immune interactions during tumour evolution result in immunoediting and immune evasion. The goal of this project is to use large cancer genome databases to identify the underlying genomic alterations, in both the untreated cancer genome and following treatment with immunomodulating agents. Results can be exploited to predict differential responses to cancer immunotherapy.