Project

Self-replicating mRNA as a platform for Campylobacter vaccination in chickens.

Duration
01 October 2019 → Ongoing
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Medical and health sciences
    • Microbiology not elsewhere classified
  • Engineering and technology
    • Medical biotechnology not elsewhere classified
  • Agricultural and food sciences
    • Veterinary medicine not elsewhere classified
Keywords
mRNA Vaccine Campylobacter broiler prophylaxis foodborne disease
 
Project description

Campylobacter jejuni is the most common cause of bacterial foodborne disease. Poultry products are considered the most important source. Campylobacter colonization in broilers might be reduced by immunization-based approaches. However, an effective vaccine is not yet available.
The ultimate goal of this project is to construct and evaluate a self-replicating mRNA Campylobacter vaccine, expressing immunodominant antigens in chickens.