Research Explorer

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Project

Modified 7-deazapurine nucleoside analogues for the treatment of human African trypanosomiasis: towards a strong proof-of-concept.

Outputs and Outcomes

Publications

Cloning and characterization of Trypanosoma congolense and T. vivax nucleoside transporters reveal the potential of P1-type carriers for the discovery of broad-spectrum nucleoside-based therapeutics against animal African trypanosomiasis

Marzuq A. UngogoMustafa M. AldferManal J. NattoHainan ZhuangRobyn ChisholmKaty WalshMarieClaire McGeeKayhan IlbeigiJamal Ibrahim AsseriRichard J. S. BurchmoreGuy CaljonSerge Van CalenberghHarry P. De Koning et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploration of 6-methyl-7-(hetero)aryl-7-deazapurine ribonucleosides as antileishmanial agents

Cai LinIzet KaralicAn MatheeussenPim-Bart FeijensFabian HulpiaLouis MaesGuy CaljonSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nucleoside analogues for the treatment of animal trypanosomiasis

Dorien MabilleKayhan IlbeigiSarah HendrickxMarzuq A. UngogoFabian HulpiaCai LinLouis MaesHarry P. de KoningSerge Van CalenberghGuy Caljon

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

N6-modification of 7-deazapurine nucleoside analogues as anti-Trypanosoma cruzi and anti-Leishmania agents : structure-activity relationship exploration and in vivo evaluation

Cai LinDenise da Gama Jaén BatistaAna Lia MazzetiRoberson Donola GirãoGabriel Melo de OliveiraIzet KaralicFabian HulpiaMaria de Nazaré C. SoeiroLouis MaesGuy CaljonSerge Van Calenbergh et al.

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents

Cai LinFabian HulpiaIzet KaralicLaurens De SchepperLouis MaesGuy CaljonSerge Van Calenbergh

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE