Rationale:
Current treatment and screening procedures following an Anterior Cruciate Ligament (ACL) rupture are falling short to cover all dysfunctions,
resulting in reinjury rates as high as 1 out of 5 in athletes returning to cutting or pivoting sports. At present, more evidence demonstrates that ACL
rupture and subsequent reconstruction (ACLR) involve not only musculoskeletal and psychological impairments, but also alter the central nervous
system (CNS). Since ACLR patients, even at return to sport (RTS), have persistently altered brain activation and aberrant, high-risk movement patterns
in situations requiring an external focus of attention, the relationship between these CNS alterations, biomechanics and the occurrence of (re)injury
could provide valuable insight to enhance current treatment and screening procedures.

Objective:
To examine the relationship between spatiotemporal dynamics of electrocortical brain activity and biomechanical performance in ACLR patients
compared to healthy individuals during soccer-specific, VR guided motor trials. In doing so, the ultimate attempt is to identify athletes at risk for ACL
(re)injury and increase the number of players safely performing at their initial level.

Work plan:
The research methodology includes three different assessments:

• A1: Electroencephalography (EEG) during three VR guided single-leg stance conditions and a non-VR guided isokinetic strength evaluation of the m.
  Quadriceps and m. Hamstrings.
• A2: Movement biomechanics during a soccer-specific, VR guided return to sport screening and a clinical counterpart of these trials.
• A3: Occurrence of (re)injury within the first year after the VR guided screening.