Research Explorer

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Project

Impact of peripheral virus infection on the central nervous system

Outputs and Outcomes

Publications

Pseudorabies virus infection triggers pUL46-mediated phosphorylation of connexin-43 and closure of gap junctions to promote intercellular virus spread

Alexander Tishchenko KhoruzhNicolás Romero RataCliff Van WaesbergheJonas L. DelvaOliver VickmanGregory A. SmithThomas C. MettenleiterWalter FuchsBarbara G. KluppHerman Favoreel

U Journal Article in PLOS Pathogens

The role of N6-methyladenosine (m6A) mRNA modifications in herpesvirus infections

Ruth VerhammeHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression

Ruth VerhammeRobert JansensJianheng LiuFien Van RaemdonckCliff Van WaesbergheLuke NicholsonSamie R. JaffreyHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

The alphaherpesvirus gE/gI glycoprotein complex and proteases jointly orchestrate invasion across the host’s upper respiratory epithelial barrier

Eline Van CrombruggeXiaolei RenSarah GlorieuxInes ZarakWim Van Den BroeckClaus BachertNan ZhangThibaut Van ZeleD. KimG. A. SmithKathlyn LavalHans Nauwynck et al.

A1 Journal Article in MBIO

Deletion of gE in herpes simplex virus 1 leads to increased extracellular virus production and augmented interferon alpha production by peripheral blood mononuclear cells

Manon ClaeysJonas DelvaCedric JacqmotteCliff Van WaesbergheHerman Favoreel

A1 Journal Article in PATHOGENS

Pseudorabies virus infection triggers mitophagy to dampen the interferon response and promote viral replication

Yuan ZhaoChan DingZhenbang ZhuWenqiang WangWei WenHerman FavoreelXiangdong Li

A1 Journal Article in JOURNAL OF VIROLOGY

Aspergillus fumigatus spore proteases alter the respiratory mucosa architecture and facilitate equine herpesvirus 1 infection

Joren PortaelsEline Van CrombruggeWim Van Den BroeckKatrien LagrouKathlyn LavalHans Nauwynck

A1 Journal Article in VIRUSES-BASEL