Project

Contrast-enhanced ultrasound imaging to evaluate the relationship between obesity and kidney disease, and to assess therapeutic effects of weight loss and nutritional management (with omega-3 fatty acids), in a dog model.

Code
01N02215
Duration
01 January 2015 → 31 October 2019
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
Keywords
obesity
 
Project description

In humans, obesity-related kidney disease tends to be an under-recognized problem. In this dog model, quantitative contrast-enhanced ultrasonography, correlated with other renal function tests, will be used to determine the (early) effects of obesity on renal perfusion. Subsequently, the therapeutic effects of weight loss and omega-3 nutritional management on renal perfusion in obese dogs will be evaluated.