This workpackage regroups multiple activities overall aiming at the determination of the expression level of GLPG targets, factors on or downstream of the target pathway and the activation level of target pathways in blood and in colon samples from IBD patients. Different conditions will be compared

Multiple techniques will be applied ranging from micro-array analysis and QPCR validation to immunehistochemistry and in situ hybridization in order to establish systemic and mucosal expression at the m RNA and protein level