Project

Cell death activity regulation in inflammation and cancer

Acronym
Cedar-ic
Code
01M00709
Duration
01 January 2009 → 30 September 2027
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Regulation of metabolism
Keywords
transgenics
 
Project description

The project aims at a global and integrated approach of the 4 major types of cell death (apoptosis, necrosis, autophagic cell death, pyroptosis) on four levels: the biochemistry of caspases and RIP kinases, the intracellular signal transduction, the intercellular communication and its role in experimental diseaese models using transgenic animals. We will use global approaches involving shRNA, siRNA and miRNA screenings, interactomics, degradomics, phosphoproteomics and bioinformatics.