Research Explorer

Project

Synthesis and characterization of non-viral liposomal carriers for the local application of siRNA molecules and antagomirs in the therapeutic treatment of psoriasis
Code
01J10211
Duration
01 July 2011 → 30 April 2014
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Dermatology
    • Medical biochemistry and metabolism
    • Dermatology
    • Medical biochemistry and metabolism
    • Dermatology
    • Medical biochemistry and metabolism
Keywords
siRNA liposomes miRNA psoriasis topical
 
Project description

The aim of this project is the development of a topical liposomal vector for the protection, transport and delivery of siRNAs and antagomirs (anti-miRNAs) to target genes important in the pathogenesis of psoriasis. By intervening at genetic level by means of a topical applied therapy, we want to create a specific, better tolerated and patient-friendly therapy for psoriasis.