Project

Combining photoporation with electrophoresis for improved transfection of hard-to-transfect cells

Code

01IO1020

Duration

01 October 2020 → 30 September 2024

Funding

Regional and community funding: Special Research Fund

Promotor

Kevin Braeckmans

Research disciplines

Medical and health sciences
- Biopharmaceuticals
- Physical pharmacy
Engineering and technology
- Semiconductor devices, nanoelectronics and technology
- Nanobiotechnology
- Nanophotonics

Keywords

Transfection cell engineering cell therapy photoporation electrophoresis T-cells cancer therapy

Project description

Intracellular delivery of high molecular weight biological molecules is a prerequisite both for fundamental cell biological research as well as for the production of engineered therapeutic cells. This project aims at substantially improving this process for hard-to-transfect cells by combining the strengths of photoporation and electrophoresis, two unrelated techniques that belong to the respective expertises of both promoters.