Project

Combining photoporation with electrophoresis for improved transfection of hard-to-transfect cells

Code
01IO1020
Duration
01 October 2020 → 30 September 2024
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Biopharmaceuticals
    • Physical pharmacy
  • Engineering and technology
    • Semiconductor devices, nanoelectronics and technology
    • Nanobiotechnology
    • Nanophotonics
Keywords
Transfection cell engineering cell therapy photoporation electrophoresis T-cells cancer therapy
 
Project description

Intracellular delivery of high molecular weight biological molecules is a prerequisite both for fundamental cell biological research as well as for the production of engineered therapeutic cells. This project aims at substantially improving this process for hard-to-transfect cells by combining the strengths of photoporation and electrophoresis, two unrelated techniques that belong to the respective expertises of both promoters.