Research Explorer

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Project

From thiazepane curcuminoid hit structures to new anticancer lead compounds

Outputs & Impact

Publications & research data ( 4 )

Curcumin-based benzothiazepane analogues exhibit selective anti-cancer activity in HCT-116 cells via precipitated particle formation and internalisation

Julie De MunckCharlotte GrootaertKatarina MagdalenicDerya DeveciYannick GansemansFilip Van NieuwerburghNico BoonAndre SkirtachAndreja RajkovicMatthias D'hooghe et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Synthesis and cancer cell cytotoxicity of 6-, 7-, or 8-substituted 2-(hetero)aryl-4-(4-(hetero)aryl-2-oxobut-3-en-1-ylidene)benzothiazepanes

Katarina MagdalenicDonatien MorillonSteven De JongheLeentje PersoonsDominique ScholsKristof Van HeckeCharlotte GrootaertJohn Van CampMatthias D'hooghe

A1 Journal Article in JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis and cancer cell cytotoxicity of 2-heteroaryl-4-(4-heteroaryl-2-oxobut-3-en-1-ylidene)-substituted benzothiazepanes

Katarina MagdalenicFelien MorlionSteven De JongheLeentje PersoonsDominique ScholsCharlotte GrootaertJohn Van CampMatthias D'hooghe

A1 Journal Article in TETRAHEDRON

Heterocycle-substituted 1,5-benzothiazepines : biological properties and structure-activity relationships

Felien MorlionKatarina MagdalenicJohn Van CampMatthias D'hooghe

A1 Journal Article in MONATSHEFTE FUR CHEMIE

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )