Project

Transcriptional regulation of human natural killer cell and innate lymphoid cell differentiation

Duration
01 October 2014 → 24 June 2019
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Genetics
  • Medical and health sciences
    • Gynaecology and obstetrics
    • Immunology
    • Molecular and cell biology
    • Morphological sciences
    • Gynaecology and obstetrics
    • Immunology
    • Molecular and cell biology
    • Morphological sciences
    • Gynaecology and obstetrics
    • Immunology
    • Molecular and cell biology
    • Morphological sciences
Keywords
hematopoiesis human stem cells gene modulation
 
Project description

In this project we will investigate the development of human natural killer cell and innate lymphoid cell development from pluripotent stem cells. Therefore, the role of transcription factors important for this process will be determined by overexpression or deletion of the gene.