Project

Tn-Miner: Technology for the discovery of tumor-specific glycopeptide immunotherapy targets.

Acronym
Tn-Miner
Code
F2022/IOF-StarTT/089
Duration
15 October 2023 → 14 April 2025
Funding
Regional and community funding: Industrial Research Fund
Research disciplines
  • Natural sciences
    • Analytical biochemistry
  • Medical and health sciences
    • Other organic elements and compounds
    • Medical proteomics
    • Cancer therapy
    • Posttranslational modifications
Keywords
cancer tumor specific epitopes Immunotherapy O-glycopeptides detection method
 
Project description

The diverse recently developed modalities for immunotherapy of cancer are limited by the very small number of sufficiently tumor-specific cell surface targets that can be targeted with antibodies. In this project, a newly invented target discovery technology is valorized, aiming to overcome this problem, especially for carcinomas.