Project

SSTR2 expression on macrophages and effect on tumor response

Code
01SC7325
Duration
01 October 2025 → 30 September 2028
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Nuclear imaging
Keywords
SSTR2 macrophages Immune checkpoint inhibitors tumor microenvironment personalized treatment
 
Project description

This research project investigates the predictive value of somatostatin subtype 2 receptor (SSTR-2)
expression in melanoma, triple-negative breast cancer, and renal cell carcinoma for immune
checkpoint inhibitor responses. Through immunohistochemical analysis and 68Ga-DOTATATE
PET/CT imaging, the study aims to correlate SSTR-2 expression with clinical outcomes, enhancing
personalized treatment strategies for these malignancies.