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Project

Cell type-specific functional analysis of inflammasome signalling in intestinal inflammation

Information

Project Team

Organisations

Outputs and Outcomes

Publications

Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion

Maria Giulia DoglioLien VerboomEmily Ruilova SosorangaUlrika FrisingTomoko AsaokaYannick GansemansFilip Van NieuwerburghGeert van LooAndy Wullaert

A1 Journal Article in SCIENCE IMMUNOLOGY

2023

Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection

Elien EeckhoutLisa HamerlinckVeronique JonckheerePetra Van DammeGeert van LooAndy Wullaert

A1 Journal Article in CELL DEATH & DISEASE

2023

Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice

Ulrika FrisingSilvia Ribó GenéMaria Giulia DoglioBernard MalissenGeert van LooAndy Wullaert

A1 Journal Article in EMBO REPORTS

2022