Research Explorer

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Project

Epigenetic drivers of human αβ and γδ T cell differentiation at the single cell level.

Outputs & Impact

Publications & research data ( 11 )

Thymic pioneers : charting the origin, identity, and fate of human thymus seeding progenitors

Kai Ling LiangLena BoehmeSilke PaepensMaryam HassanTom Taghon

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

From cortex to medulla : navigating the thymic landscape of T cell education

Lena BoehmeNadav YayonSarah A. TeichmannTom Taghon

Editorial material

A spatial human thymus cell atlas mapped to a continuous tissue axis

Nadav YayonVeronika R. KedlianLena BoehmeChenqu SuoBrianna T. WachterRebecca T. BeuschelOren AmsalemKrzysztof PolanskiSimon KoplevElizabeth Tuck et al.

A1 Journal Article in NATURE

A spatial human thymus cell atlas mapped to a continuous tissue axis

Nadav YayonVeronika R. KedlianLena BöhmeChenqu SuoBrianna WachterRebecca T. BeuschelOren AmsalemKrzysztof PolanskiSimon KoplevElizabeth Tuck et al.

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF

Kai Ling LiangJuliette RoelsMarieke LavaertTom PuttemanLena BoehmeLaurentijn TillemanImke VelgheValentina PegorettiInge Van de WalleStephanie Sontag et al.

A1 Journal Article in NATURE IMMUNOLOGY

Dendritic cell-biased precursors support early human thymopoiesis

Tom TaghonKai Ling Liang

Editorial material

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore BillietLaurenz De CockGuillem Sanchez SanchezRupert MayerGlenn GoetgelukStijn De MunterMelissa PilleJoline IngelsHanne JansenKarin Weening et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Identification and purification of human T cell precursors

Inge Van de WalleNina LambrechtsAnaïs DerveeuwMarieke LavaertJuliette RoelsTom Taghon

Bookchapter in T-cell development : methods and protocols

In vitro model systems to study human T cell development

Nina LambrechtsKai Ling LiangImke VelgheSteven StrubbeAnne-Catherine DolensTom Taghon

Bookchapter in T-cell development : methods and protocols

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

Juliette RoelsJolien Van HulleMarieke LavaertAnna KuchmiySteven StrubbeTom PuttemanBart VandekerckhoveGeorges LeclercqFilip Van NieuwerburghLena Boehme et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Development of gamma delta T cells in the thymus : a human perspective

Lena BöhmeJuliette RoelsTom Taghon

A1 Journal Article in SEMINARS IN IMMUNOLOGY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )