Research Explorer

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Project

Unraveling the heterogeneity of the choroid plexus tissue and its cell (sub)type-specific response to different inflammatory triggers.

Outputs & Impact

Publications & research data ( 8 )

Base barrier cells provide compartmentalization of choroid plexus, brain and CSF

Daan VerhaegeClint De NolfLore Van AckerWouter ClaeysJonas CasteleinElien Van WonterghemGriet Van ImschootPieter DujardinWard De SpiegelaereEsther Hoste et al.

U Journal Article in NATURE NEUROSCIENCE

The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles

Junhua XieLien Van HoeckeElien Van WonterghemGriet Van ImschootVanessa AndriesLars VereeckeRoosmarijn Vandenbroucke

A1 Journal Article in GUT MICROBES

Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease : lessons from animal studies

Wouter ClaeysAnja GeertsLien Van HoeckeChristophe Van SteenkisteRoosmarijn Vandenbroucke

A1 Journal Article in NEURAL REGENERATION RESEARCH

An immunological puzzle : the adaptive immune system fuels Alzheimer’s disease pathology

Lien Van HoeckeJonas CasteleinJunhua XieLore Van AckerGriet Van ImschootElien Van WonterghemIne VlaeminckDaan VerhaegeWouter ClaeysKeimpe Wierda et al.

A1 Journal Article in BRAIN BEHAVIOR AND IMMUNITY

Limitations of PLX3397 as a microglial investigational tool : peripheral and off-target effects dictate the response to inflammation

Wouter ClaeysDaan VerhaegeGriet Van ImschootElien Van WonterghemLore Van AckerLaura AmelinckFederico Francesco De PontiCharlotte ScottAnja GeertsChristophe Van Steenkiste et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology

Junhua XieArnout BruggemanClint De NolfCharysse VandendriesscheGriet Van ImschootElien Van WonterghemLars VereeckeRoosmarijn Vandenbroucke

A1 Journal Article in EMBO JOURNAL

Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling

Junhua XieLien CoolsGriet Van ImschootElien Van WonterghemMarie PauwelsIne VlaeminckChloë De WitteSamir EL AndaloussiKeimpe WierdaLies De Groef et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The impact of systemic inflammation on Alzheimer's disease pathology

Junhua XieLien Van HoeckeRoosmarijn Vandenbroucke

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )