Research Explorer

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Project

Development and implementation of analytical methods based on laser ablation – and single-event ICP-mass spectrometry for examining metal(loid) signatures in cancer

Outputs and Outcomes

Publications

Quantitative determination and subcellular mapping of Pt-based drugs in single breast tumour cells via laser ablation-ICP-mass spectrometry

Legna Colina VegasThibaut Van AckerWilmer VillarrealOlivier De WeverAlzir Azevedo BatistaJoaquim Araújo NóbregaFrank Vanhaecke

A1 Journal Article in DALTON TRANSACTIONS

An evaluation of the analytical and biological robustness of a method for quantifying iron in individual red blood cells via single-cell tandem ICP-mass spectrometry

Rinus DejongheEduardo Bolea FernandezAna Lores PadínThibaut Van AckerAna Maria Rua IbarzOlivier De WeverFrank Vanhaecke

A1 Journal Article in MICROCHEMICAL JOURNAL

Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data

Cláudio PinheiroNiké GuilbertLien LippensQuentin RouxRobin BoiySuzanne FischerSofie Van DorpeBram De CraeneGeert BerxTom BoterbergGwen SysHannelore DenysIlkka MiinalainenPieter MestdaghJo VandesompeleOlivier De WeverAn Hendrix et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Evaluation of two-phase sample transport upon ablation of gelatin as a proxy for soft biological matrices using nanosecond laser ablation – inductively coupled plasma – mass spectrometry

Tom Van HeldenKristina MervičIvan NemetJohannes T. van ElterenFrank VanhaeckeSanda RončevićMartin ŠalaThibaut Van Acker

A1 Journal Article in ANALYTICA CHIMICA ACTA

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila CobosJan KosterFranco Alexander Poma SotoJasper VerwiltJasper AnckaertJilke De WildeCarolina FierroPhilippe DecruyenaereJill DeleuBert DhondtEva HulstaertNele NijsJustine NuytensAnnouck PhilippronKathleen SchoofsEveline Vanden EyndeKimberly VerniersNurten YigitThibaut D'huyvetterThomas PiofczykOlivier ThasScott KuerstenTim R MercerGary P SchrothKatleen De PreterTom Van Maerken et al.

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De VlieghereKoen Van de VijverEva BlondeelNathan CarpentierRouba GhobeiraJarne PauwelsSebastian RiemannManon MinsartCharlotte FieuwsJohanna MestachAns BaeyensNathalie De GeyterCharlotte DebbautHannelore DenysBenedicte DescampsKathleen ClaesAnne VralJo Van DorpeKris GevaertBruno De GeestWim CeelenSandra Van VlierbergheOlivier De Wever et al.

A1 Journal Article in BIOMATERIALS RESEARCH

Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility

Sofie Van DorpeLien LippensRobin BoiyCláudio PinheiroGlenn VergauwenPekka RappuIlkka MiinalainenPhilippe TummersHannelore DenysOlivier De WeverAn Hendrix et al.

A1 Journal Article in JOURNAL OF NANOBIOTECHNOLOGY

Depletion of soluble cytokines unlocks the immunomodulatory bioactivity of extracellular vesicles

Quentin RouxRobin BoiyFelix De VuystMercedes TkachCláudio PinheiroSofie De GeyterIlkka MiinalainenClotilde TheryOlivier De WeverAn Hendrix

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics

Bert DhondtCláudio PinheiroEdward GeeurickxJoeri TulkensGlenn VergauwenEdwin Van Der PolRienk NieuwlandAnneleen DecockIlkka MiinalainenPekka RappuGary SchrothScott KuerstenJo VandesompelePieter MestdaghNicolaas LumenOlivier De WeverAn Hendrix et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Analysis of microsamples of biological fluids via inductively coupled plasma-tandem mass spectrometry using a micro-flow injection system coupled to a high-efficiency sample introduction setup

Tong LiuEduardo Bolea FernandezFrank Vanhaecke

A1 Journal Article in SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY

Living in a transient world : ICP-MS reinvented via time-resolved analysis for monitoring single events

M. ResanoM. AramendíaE. García-RuizA. BazoEduardo Bolea FernandezFrank Vanhaecke

A1 Journal Article in CHEMICAL SCIENCE

MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity

Arne PeirsmanEva BlondeelTasdiq AhmedJasper AnckaertDominique AudenaertTom BoterbergKrisztina BuzasNeil CarragherGastone CastellaniFlávia CastroVirginie Dangles-MarieJohn DawsonPascal De TullioElly De VlieghereSandor DedeyneHerman DepypereAkos DiosdiRuslan DmitrievHelmut DolznigSuzanne FischerChristian GespachVera GoossensJyrki HeinoAn HendrixPeter HorvathLeoni A. Kunz-SchughartSebastiaan MaesChristophe MangodtPieter MestdaghSoňa MichlíkováMaria José OliveiraFrancesco PampaloniFilippo PiccininiCláudio PinheiroJennifer RahnStephen M. RobbinsElina SiljamäkiPatrick SteigemannGwen SysShuichi TakayamaAnna TeseiJoeri TulkensMichiel Van WaeyenbergeJo VandesompeleGlenn WagemansClaudia WeindorferNurten YigitNina ZablowskyMichele ZanoniPhillip BlondeelOlivier De Wever et al.

A1 Journal Article in NATURE METHODS

Single-event tandem ICP-mass spectrometry for the quantification of chemotherapeutic drug-derived Pt and endogenous elements in individual human cells

Tong LiuEduardo Bolea FernandezChristophe MangodtOlivier De WeverFrank Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

Analytical figures of merit of a low-dispersion aerosol transport system for high-throughput LA-ICP-MS analysis

Thibaut Van AckerStijn Van MalderenTom Van HeldenCiprian StremtanMartin ŠalaJohannes T. van ElterenFrank Vanhaecke

A1 Journal Article in JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY