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Project
Development and implementation of analytical methods based on laser ablation – and single-event ICP-mass spectrometry for examining metal(loid) signatures in cancer
Information
Project Team
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Outputs & Impact
Publications & research data ( 18 )
From pitfalls to progress in quantitative single-cell elemental analysis by time-of-flight ICP-mass spectrometry
Rinus Dejonghe
Ana Lores Padín
Eduardo Bolea Fernandez
Thibaut Van Acker
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
2026
Improving transport efficiency for large human cells for enabling accurate determination of cellular nanoparticle uptake via SC-ICP-TOF-MS
Mina Nikolić
Ana Lores Padín
Thibaut Van Acker
Tina Smets
Ilia Goemaere
Amin Ahmad
Kevin Braeckmans
Eduardo Bolea Fernandez
Frank Vanhaecke
A1
Journal Article
in
TALANTA
2026
Boosting the pixel acquisition rate of elemental mapping with laser ablation-ICP-mass spectrometry to 1000 Hz
Iker Basabe Mendizabal
Ryoga Maeda
Steven Goderis
Frank Vanhaecke
Thibaut Van Acker
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2025
Predicting image quality degradation as a result of two-phase sample transport in LA-ICP-TOFMS mapping of carbon-based materials
Johannes T. van Elteren
Tom Van Helden
Dino Metarapi
Thibaut Van Acker
Kristina Mervič
Martin Šala
Frank Vanhaecke
A1
Journal Article
in
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
2025
Quantitative determination and subcellular mapping of Pt-based drugs in single breast tumour cells via laser ablation-ICP-mass spectrometry
Legna Colina Vegas
Thibaut Van Acker
Wilmer Villarreal
Olivier De Wever
Alzir Azevedo Batista
Joaquim Araújo Nóbrega
Frank Vanhaecke
A1
Journal Article
in
DALTON TRANSACTIONS
2024
An evaluation of the analytical and biological robustness of a method for quantifying iron in individual red blood cells via single-cell tandem ICP-mass spectrometry
Rinus Dejonghe
Eduardo Bolea Fernandez
Ana Lores Padín
Thibaut Van Acker
Ana Maria Rua Ibarz
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
MICROCHEMICAL JOURNAL
2024
Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data
Cláudio Pinheiro
Niké Guilbert
Lien Lippens
Quentin Roux
Robin Boiy
Suzanne Fischer
Sofie Van Dorpe
Bram De Craene
Geert Berx
Tom Boterberg
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2024
Evaluation of two-phase sample transport upon ablation of gelatin as a proxy for soft biological matrices using nanosecond laser ablation – inductively coupled plasma – mass spectrometry
Tom Van Helden
Kristina Mervič
Ivan Nemet
Johannes T. van Elteren
Frank Vanhaecke
Sanda Rončević
Martin Šala
Thibaut Van Acker
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2024
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conference
2023
A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment
Elly De Vlieghere
Koen Van de Vijver
Eva Blondeel
Nathan Carpentier
Rouba Ghobeira
Jarne Pauwels
Sebastian Riemann
Manon Minsart
Charlotte Fieuws
Johanna Mestach
et al.
A1
Journal Article
in
BIOMATERIALS RESEARCH
2023
Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility
Sofie Van Dorpe
Lien Lippens
Robin Boiy
Cláudio Pinheiro
Glenn Vergauwen
Pekka Rappu
Ilkka Miinalainen
Philippe Tummers
Hannelore Denys
Olivier De Wever
et al.
A1
Journal Article
in
JOURNAL OF NANOBIOTECHNOLOGY
2023
Depletion of soluble cytokines unlocks the immunomodulatory bioactivity of extracellular vesicles
Quentin Roux
Robin Boiy
Felix De Vuyst
Mercedes Tkach
Cláudio Pinheiro
Sofie De Geyter
Ilkka Miinalainen
Clotilde Thery
Olivier De Wever
An Hendrix
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2023
Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics
Bert Dhondt
Cláudio Pinheiro
Edward Geeurickx
Joeri Tulkens
Glenn Vergauwen
Edwin Van Der Pol
Rienk Nieuwland
Anneleen Decock
Ilkka Miinalainen
Pekka Rappu
et al.
A1
Journal Article
in
JOURNAL OF EXTRACELLULAR VESICLES
2023
Analysis of microsamples of biological fluids via inductively coupled plasma-tandem mass spectrometry using a micro-flow injection system coupled to a high-efficiency sample introduction setup
Tong Liu
Eduardo Bolea Fernandez
Frank Vanhaecke
A1
Journal Article
in
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
2022
Living in a transient world : ICP-MS reinvented via time-resolved analysis for monitoring single events
M. Resano
M. Aramendía
E. García-Ruiz
A. Bazo
Eduardo Bolea Fernandez
Frank Vanhaecke
A1
Journal Article
in
CHEMICAL SCIENCE
2022
MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity
Arne Peirsman
Eva Blondeel
Tasdiq Ahmed
Jasper Anckaert
Dominique Audenaert
Tom Boterberg
Krisztina Buzas
Neil Carragher
Gastone Castellani
Flávia Castro
et al.
A1
Journal Article
in
NATURE METHODS
2021
Single-event tandem ICP-mass spectrometry for the quantification of chemotherapeutic drug-derived Pt and endogenous elements in individual human cells
Tong Liu
Eduardo Bolea Fernandez
Christophe Mangodt
Olivier De Wever
Frank Vanhaecke
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2021
Analytical figures of merit of a low-dispersion aerosol transport system for high-throughput LA-ICP-MS analysis
Thibaut Van Acker
Stijn Van Malderen
Tom Van Helden
Ciprian Stremtan
Martin Šala
Johannes T. van Elteren
Frank Vanhaecke
A1
Journal Article
in
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
2021
Activities ( 0 )
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Impact narratives ( 0 )
Patents ( 0 )