Research Explorer

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Project

High intensity focused ultrasound and mRNA nanomedicines: a new strategy to induce and boost anti-tumor immunity

Outputs & Impact

Publications & research data ( 23 )

Sequence simplification of antigen coding IVT mRNA allows accelerated synthetic DNA template generation and epitope immunogenicity validation

Arthur EspritDorien AutaersIlke AernoutIne LentackerSteve PascoloKris ThielemansKarine BreckpotLorenzo Franceschini

A1 Journal Article in MOLECULAR THERAPY NUCLEIC ACIDS

Immunogenic cell death as interplay between physical anticancer modalities and immunotherapy

Yanou EngelenRobin DemuynckJana RamonK. BreckpotStefaan De SmedtGuillaume LajoinieKevin BraeckmansDmitri KryskoIne Lentacker

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Preclinical toxicological assessment of an α-galactosylceramide-adjuvanted mRNA cancer vaccine in Wistar Han rats and domestic pigs

Sofie MeulewaeterMargo De VelderDiethard ReckelbusKevin MwangiThomas EhouarneIlke AernoutYanou EngelenFëllanza HalimiIsis Van herteryckLobke De Bels et al.

A1 Journal Article in MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT

Immunogenicity of cell death and cancer immunotherapy with immune checkpoint inhibitors

Elena CatanzaroManuel Beltran-VisiedoLorenzo GalluzziDmitri Krysko

A1 Journal Article in CELLULAR & MOLECULAR IMMUNOLOGY

Optimizing high-intensity focused ultrasound-induced immunogenic cell-death using passive cavitation mapping as a monitoring tool

Yanou EngelenDmitri KryskoIuliia EfimovaKarine BreckpotMichel VersluisStefaan De SmedtGuillaume LajoinieIne Lentacker

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

CX3CL1 release during immunogenic apoptosis is associated with enhanced anti-tumour immunity

Faye NaessensRobin DemuynckOlga VershininaIuliia EfimovaMariia SaviukGreet De SmetTatiana A. MishchenkoMaria V. VedunovaOlga KryskoElena Catanzaro et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Nanomedicine to aid immunogenic cell death (ICD)-based anticancer therapy

Robin DemuynckYanou EngelenAndre SkirtachStefaan De SmedtIne LentackerDmitri Krysko

A1 Journal Article in TRENDS IN CANCER

Immunogenicity of ferroptosis in cancer : a matter of context?

Elena CatanzaroRobin DemuynckFaye NaessensLorenzo GalluzziDmitri Krysko

A1 Journal Article in TRENDS IN CANCER

Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics

Jana RamonYanou EngelenHerlinde De KeersmaeckerIlia GoemaereDeep PunjJulián Mejía MoralesCédric BonteGeert BerxEsther HosteStephan Stremersch et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Peripheral blood lymphocytes differ in DNA damage response after exposure to X-rays with different physical properties

Simon SioenLouise D'hondtFien Van HouteRobin DemuynckKlaus BacherCarlos De WagterAnne VralBarbara VanderstraetenDmitri KryskoAns Baeyens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium

Joke DeprezRein VerbekeSofie MeulewaeterIlke AernoutHeleen DewitteTine DecruyJulie CoudenysJulie Van DuyseGert Van IsterdaelDan Peer et al.

A1 Journal Article in NATURE NANOTECHNOLOGY

Mechanobiology of ferroptotic cancer cells as a novel 'eat-me' signal : regulating efferocytosis through layer-by-layer coating

Louis Van der MeerenIuliia EfimovaRobin DemuynckBogdan ParakhonskiyDmitri KryskoAndre Skirtach

A1 Journal Article in ADVANCED HEALTHCARE MATERIALS

Ferroptosis : friend or foe in cancer immunotherapy?

Robin DemuynckIuliia EfimovaElena CatanzaroDmitri Krysko

Editorial material

Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy

Elena CatanzaroEleonora TurriniTessa KerreSimon SioenAns BaeyensAlessandra GuerriniMohamed Lamin Abdi BellauGianni SacchettiGuglielmo PaganettoDmitri Krysko et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation

Olga KryskoJoshua H. BourneElena KondakovaElena A. GalovaKatharine WhitworthMaddy L. NewbyClaus BachertHarriet HillMax CrispinZania Stamataki et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

In vitro veritas : from 2D cultures to organ-on-a-chip models to study immunogenic cell death in the tumor microenvironment

Dmitri KryskoRobin DemuynckIuliia EfimovaFaye NaessensOlga KryskoElena Catanzaro

A1 Journal Article in CELLS

DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

Maria VedunovaVictoria TurubanovaOlga VershininaMariia SaviukIuliia EfimovaTatiana MishchenkoRobrecht RaedtAnne VralChristian VanhoveDaria Korsakova et al.

A1 Journal Article in CELL DEATH & DISEASE

Immunogenic cell death and role of nanomaterials serving as therapeutic vaccine for personalized cancer immunotherapy

Elena CatanzaroOlivier FeronAndre SkirtachDmitri Krysko

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Which cell death modality wins the contest for photodynamic therapy of cancer?

Tatiana MishchenkoIrina BalalaevaAnastasia GorokhovaMaria VedunovaDmitri Krysko

A1 Journal Article in CELL DEATH & DISEASE

Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer

Ragna HaegebaertMaxime KempersWim CeelenIne LentackerKatrien Remaut

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across

An-Katrien MinnaertHelena VanlucheneRein VerbekeIne LentackerStefaan De SmedtKoen RaemdonckNiek SandersKatrien Remaut

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Immunogenic ferroptosis and where to find it?

Robin DemuynckIuliia EfimovaFaye NaessensDmitri Krysko

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

Opening doors with ultrasound and microbubbles : beating biological barriers to promote drug delivery

Joke DeprezG. LajoinieYanou EngelenStefaan De SmedtIne Lentacker

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )