Research Explorer

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Project

Dissecting the molecular signals that drive immunogenic versus homeostatic maturation in dendritic cells. An old question revisited.

Outputs and Outcomes

Publications

Lipid Nanoparticles as a Tool to Dissect Dendritic Cell Maturation Pathways

Sofie RennenVictor BosteelsClint De NolfGreta WebbKaro Van LilSandra MaréchalJessica VettersEvelien Van De VeldeFarzaneh FayazpourRia RoelandtNiels VandammeKevin VerstaenStefaan De SmedtKarine BreckpotBruno De GeestRein VerbekeIne LentackerSophie Janssens et al.

Striking a balance : new perspectives on homeostatic dendritic cell maturation

Victor BosteelsSophie Janssens

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

The unfolded protein sensor IRE1a is essential for homeostatic dendritic cell maturation

Sophie JanssensVictor BosteelsSandra MaréchalEva ClootsLaurien Van HeddegemSimon TavernierSofie RennenClint De NolfSeraja AmstelveenJonathan MaelfaitLiesbet MartensEvelien Van De VeldeFarzaneh FayazpourKim DeswarteWouter SaelensLouis BoonJulie Van DuyseGert Van IsterdaelIsabelle GuillasYvan SaeysBart LambrechtPieter MestdaghWilfried Le Goff et al.

Automated antibody dispensing to improve high-parameter flow cytometry throughput and analysis

Victor BosteelsJulie Van DuyseElien RuyssinckKatrien Van Der BorghtLong NguyenJannes GavelSophie JanssensGert Van Isterdael

A1 Journal Article in CYTOMETRY PART A

Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown

Quentin ReuschléLaurien Van HeddegemVictor BosteelsMatthieu MoncanSabine DepauwNadège WadierSandra MaréchalClint De NolfVirginia DelgadoYosra MessaiMarie-Claude StolzenbergAude MagérusAngélique WerckJérôme OlagneQuan LiGuillaume LefevreAnne-Sophie KorganowFrédéric Rieux-LaucatSophie JanssensPauline Soulas-Sprauel et al.

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

Decoding immunogenic cell death from a dendritic cell perspective

Sophie JanssensSofie RennenPatrizia Agostinis

A1 Journal Article in IMMUNOLOGICAL REVIEWS

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim DeswarteAlexander LamootJulie Van DuyseLiesbet MartensCedric BosteelsRia RoelandtAnnelies EmmaneelSofie Van GassenLouis BoonGert Van IsterdaelIsabelle GuillasNiels VandammeDoris HöglingerBruno De GeestWilfried Le GoffYvan SaeysKodi RavichandranBart LambrechtSophie Janssens et al.

A1 Journal Article in SCIENCE IMMUNOLOGY