Project

Toll-like receptor 3 (TLR3) stimulation in the treatment of cancer

Duration
01 January 2010 → 31 December 2010
Funding
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
Keywords
signal transduction TLR3 cancer
 
Project description

TLR3 stimulation is potentially important in the treatment of cancer. It has the potential to increase the efficiency of anti-cancer vaccines, and is also directly cytotoxic for tumor cells. In this project we study TLR3-induced signal transduction and mechanisms responsible for TLR3 resistance.