The EU is behind various initiatives and innovations to help combat climate change and embrace Green Deal goals. One of these is the creation of positive clean energy districts (PCEDs) as a means towards accelerating the transition to climate neutrality. The EU-funded NEUTRALPATH project will demonstrate the benefits of PCEDs, particularly those based on human-centred and co-creation principles as a feasible and cost-effective way to achieve emissions reduction by 2030. The project will demonstrate the efficiency of PCEDs in two cities, Zaragoza (Spain) and Dresden (Germany), and will ensure the replicability of methods, technologies and business models in other EU cities, starting in Ghent (Belgium), Istanbul (Turkey) and Vantaa (Finland).