Project

Mycobacterium tuberculosis in a cholesterol and fatty acid rich environment: global response to dormancy and antibiotic resistance

Duration
01 August 2014 → 30 September 2018
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
M. tuberculosis dormancy model drug susceptibility
 
Project description

Little is still known on the role of lipids in the survival of Mycobacterium tuberculosis. The general objective of this research project is to determine and analyze the global genetic expression of M. tuberculosis and to evaluate its drug susceptibility in an in vitro latency model in the presence of lipids cholesterol and fatty acids.