Project

Mycobacterium tuberculosis in a cholesterol and fatty acid rich environment: global response to dormancy and antibiotic resistance

Code
01W01514
Looptijd
01-08-2014 → 30-09-2018
Financiering
Regional and community funding: Special Research Fund
Onderzoeksdisciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Trefwoorden
dormantiemodel M. tuberculosis antibioticumgevoeligheid
 
Projectomschrijving

Little is still known on the role of lipids in the survival of Mycobacterium tuberculosis. The general objective of this research project is to determine and analyze the global genetic expression of M. tuberculosis and to evaluate its drug susceptibility in an in vitro latency model in the presence of lipids cholesterol and fatty acids.